Fresh on the heels of Cyberbike’s Nintendo Wii bicycle game, we find this: Honda’s Bicycle Simulator, which goes on sale in February 2010.
Aimed the educational crowd, it’s meant to safely simulate riding a bike on public streets to teach riders the rules of the road in a controlled environment.  Several sessions/lessons include “going to school”, “going to the grocery store” and “going to a local shopping street.”
Judging by the side of the road the bike’s in on the screen, it’s likely not targeted as the U.S. market.  Good thing, because that rear speaker would have to simulate rednecks yelling something stupid as they fly by in their crappy pick up.